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Posology: Inject a single dose of OSTENIL PLUS into the affected joint. The treatment effect will persist for up to 6 months. Several joints may be treated at the same time: Based on clinical studies, up to 3 consecutive doses can be given at 1-2 week interval.
No adaptations of dose or posology are required in elderly patients or patients with renal or hepatic insufficiency.
Paediatric population: No data are available.
Method of administration: For intraarticular use.
The content and the outer surface of the OSTENIL PLUS pre-filled syringe are sterile as long as the sterile pack is intact.
Take the pre-filled syringe out of the sterile pack.
Unscrew the Luer-Lok tip cap from the syringe.
Attach a suitable needle (for example 18 to 25G) and secure it by turning slightly.
Remove any air bubble, if present, before injection.
OSTENIL PLUS should be injected accurately into the joint cavity, if necessary under imaging control such as ultrasound. Avoid injections into blood vessels or surrounding tissues. In case of prior joint effusion, it is advisable to reduce the effusion by aspiration, rest, application of an ice pack and/or intraarticular corticosteroid injection. Treatment with OSTENIL PLUS can be started when the effusion has clinically resolved, or at least one week later in case of intraarticular corticosteroid injection. This interval is intended to reduce the potential risk of infection associated with intraarticular corticosteroids.
